rOpenSci | Data Visualization

Data Visualization

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Interactive, Complex Heatmaps

Alan O'Callaghan
Description

Make complex, interactive heatmaps. iheatmapr includes a modular system for iteratively building up complex heatmaps, as well as the iheatmap() function for making relatively standard heatmaps.

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Scientific use cases
  1. Gershanov, S., Toledano, H., Michowiz, S., Barinfeld, O., Pinhasov, A., Goldenberg-Cohen, N., & Salmon-Divon, M. (2018). MicroRNA&ndash,mRNA expression profiles associated with medulloblastoma subgroup 4. Cancer Management and Research, Volume 10, 339–352. https://doi.org/10.2147/cmar.s156709
  2. Ruiz, J. L., Tena, J. J., Bancells, C., Cortés, A., Gómez-Skarmeta, J. L., & Gómez-Díaz, E. (2018). Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum. Nucleic Acids Research. https://doi.org/10.1093/nar/gky643
  3. Ott, C. J., Federation, A. J., Schwartz, L. S., Kasar, S., Klitgaard, J. L., Lenci, R., … Bradner, J. E. (2018). Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell. https://doi.org/10.1016/j.ccell.2018.11.001
  4. Kim, K. W., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., … Colman, P. G. (2019). Distinct gut virome profile of pregnant women with type 1 diabetes in the ENDIA study. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofz025
  5. Reyes, A. L. P., Silva, T. C., Coetzee, S. G., Plummer, J. T., Davis, B. D., Chen, S., … Jones, M. R. (2019). GENAVi: a shiny web application for gene expression normalization, analysis and visualization. BMC Genomics, 20(1). https://doi.org/10.1186/s12864-019-6073-7
  6. Kim, K. W., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., … Colman, P. G. (2020). Higher frequency of vertebrate‐infecting viruses in the gut of infants born to mothers with type 1 diabetes. Pediatric Diabetes, 21(2), 271–279. https://doi.org/10.1111/pedi.12952
  7. Meng, S., Zhan, S., Dou, W., & Ge, W. (2019). The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis. Proteome Science, 17(1). https://doi.org/10.1186/s12953-019-0156-x
  8. Shi, L., Tian, H., Wang, P., Li, L., Zhang, Z., Zhang, J., & Zhao, Y. (2020). Spaceflight and simulated microgravity suppresses macrophage development via altered RAS/ERK/NFκB and metabolic pathways. Cellular & Molecular Immunology. https://doi.org/10.1038/s41423-019-0346-6
  9. Caseys, C., Gongjun Shi, Nicole Soltis, Raoni Gwinner, Jason Corwin, Susanna Atwell, Daniel Kliebenstein. 2020. Quantitative interactions drive Botrytis cinerea disease outcome across the plant kingdom. bioRxiv preprint 507491; https://doi.org/10.1101/507491
  10. Wang, Y., Zhang, X., Song, Q., Hou, Y., Liu, J., Sun, Y., & Wang, P. (2020). Characterization of the chromatin accessibility in an Alzheimer’s disease (AD) mouse model. Alzheimer’s Research & Therapy, 12(1). https://doi.org/10.1186/s13195-020-00598-2

Preliminary Visualisation of Data

Nicholas Tierney
Description

Create preliminary exploratory data visualisations of an entire dataset to identify problems or unexpected features using ggplot2.

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Scientific use cases
  1. Tierney, N. (2017). visdat: Visualising Whole Data Frames. The Journal of Open Source Software, 2(16), 355. https://doi.org/10.21105/joss.00355
  2. Tierney, N. J., & Cook, D. H. (2018). Expanding tidy data principles to facilitate missing data exploration, visualization and assessment of imputations. arXiv preprint arXiv:1809.02264. https://arxiv.org/abs/1809.02264
  3. Stuijfzand, S., Garthus-Niegel, S., & Horsch, A. (2020). Parental Birth-Related PTSD Symptoms and Bonding in the Early Postpartum Period: A Prospective Population-Based Cohort Study. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.570727
  4. Borg, D. N., Nguyen, R., & Tierney, N. J. (2020). Missing Data: Current Practice in Football Research and Recommendations for Improvement. https://doi.org/10.31236/osf.io/fhwcu